skbio.sequence.RNA.concat

classmethod RNA.concat(sequences, how='strict')[source]

Concatenate an iterable of Sequence objects.

State: Experimental as of 0.4.1.

Parameters
  • sequences (iterable (Sequence)) – An iterable of Sequence objects or appropriate subclasses.

  • how ({'strict', 'inner', 'outer'}, optional) – How to intersect the positional_metadata of the sequences. If ‘strict’: the positional_metadata must have the exact same columns; ‘inner’: an inner-join of the columns (only the shared set of columns are used); ‘outer’: an outer-join of the columns (all columns are used: missing values will be padded with NaN).

Returns

The returned sequence will be an instance of the class which called this class-method.

Return type

Sequence

Raises
  • ValueError – If how is not one of: ‘strict’, ‘inner’, or ‘outer’.

  • ValueError – If how is ‘strict’ and the positional_metadata of each sequence does not have the same columns.

  • TypeError – If the sequences cannot be cast as the calling class.

Notes

The sequence-wide metadata (Sequence.metadata) is not retained during concatenation.

Sequence objects can be cast to a different type only when the new type is an ancestor or child of the original type. Casting between sibling types is not allowed, e.g. DNA -> RNA is not allowed, but DNA -> Sequence or Sequence -> DNA would be.

Examples

Concatenate two DNA sequences into a new DNA object:

>>> from skbio import DNA, Sequence
>>> s1 = DNA("ACGT")
>>> s2 = DNA("GGAA")
>>> DNA.concat([s1, s2])
DNA
--------------------------
Stats:
    length: 8
    has gaps: False
    has degenerates: False
    has definites: True
    GC-content: 50.00%
--------------------------
0 ACGTGGAA

Concatenate DNA sequences into a Sequence object (type coercion):

>>> Sequence.concat([s1, s2])
Sequence
-------------
Stats:
    length: 8
-------------
0 ACGTGGAA

Positional metadata is conserved:

>>> s1 = DNA('AcgT', lowercase='one')
>>> s2 = DNA('GGaA', lowercase='one',
...          positional_metadata={'two': [1, 2, 3, 4]})
>>> result = DNA.concat([s1, s2], how='outer')
>>> result
DNA
---------------------------
Positional metadata:
    'one': <dtype: bool>
    'two': <dtype: float64>
Stats:
    length: 8
    has gaps: False
    has degenerates: False
    has definites: True
    GC-content: 50.00%
---------------------------
0 ACGTGGAA
>>> result.positional_metadata
     one  two
0  False  NaN
1   True  NaN
2   True  NaN
3  False  NaN
4  False  1.0
5  False  2.0
6   True  3.0
7  False  4.0